The PanCareSurPass project aims to improve survivorship care for children and adolescents diagnosed with cancer across Europe. Despite an 80% survival rate, significant disparities in follow-up care persist. To address this, the project introduces the SurPass v2.0 digital survivorship passport in clinics across Austria, Belgium, Germany, Italy, Lithuania, and Spain. This abstract outlines the development of a health economic evaluation framework to assess the implementation of SurPass v2.0, supported by the EU Horizon 2020 program. The framework serves two main purposes: (1) to compare the outcomes and costs of SurPass v2.0 implementation, and (2) to support evidence-based decision-making at local, regional, and national levels.